Article
The role of p53 in treatment responses of lung cancer.
Biochemical and biophysical research communications - 10 Jun 2005
Viktorsson Kristina, De Petris Luigi, Lewensohn Rolf
Abstract excerpt
Resistance to radio- and chemotherapy is a major problem in treatment responses of lung cancer. In this disease, biological markers, that can be predictive of response to treatment for guiding clinical practice, still need to be validated. Radiotherapy and most chemotherapeutic agents directly target DNA and in response to such therapies, p53 functions as a coordinator of the DNA repair process, cell cycle...
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