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Article

WIPI-Mediated Autophagy and Longevity

22 May 2015

Abstract excerpt

Autophagy is a lysosomal degradation process for cytoplasmic components, including organelles, membranes, and proteins, and critically secures eukaryotic cellular homeostasis and survival. Moreover, autophagy-related (ATG) genes are considered essential for longevity control in model organisms. Central to the regulatory relationship between autophagy and longevity is the control of insulin/insulin-like growth...

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Share to Autophagy in Disease and Therapy
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PMID: 26010754
DOI: 10.3390/cells4020202

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