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Article

Thiacremonone Potentiates Anti-Oxidant Effects to Improve Memory Dysfunction in an APP/PS1 Transgenic Mice Model.

Molecular neurobiology - 1 May 2016

Yun Hyung-Mun, Jin Peng, Park Kyung-Ran, Hwang JaeRyun, Jeong Heon-Sang, Kim Eun-Cheol, Jung Jea-Kyung, Oh Ki-Wan, Hwang Bang Yeon, Han Sang Bae, Hong Jin Tae

Abstract excerpt

Alzheimer's disease (AD) is pathologically characterized by excessive accumulation of amyloid-beta (Aβ) peptide. Evidence suggests that amyloid accumulation can be caused by oxidative stress and inflammatory responses. In this study, we examined neuroprotective effects of thiacremonone, an anti-oxidant and anti-inflammatory compound isolated from garlic. Treatment of thiacremonone significantly attenuated...

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Share to Amyloid beta-Protein Precursor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26008621
DOI: 10.1007/s12035-015-9208-0

Genes

APP
PRDX6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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