Article
Complement genetics and susceptibility to inflammatory disease. Lessons from genotype-phenotype correlations.
Immunobiology - 1 Jun 2016
de Córdoba Santiago Rodríguez
Abstract excerpt
Different genome-wide linkage and association studies performed during the last 15 years have associated mutations and polymorphisms in complement genes with different diseases characterized by tissue damage and inflammation. These are complex disorders in which genetically susceptible individuals usually develop the pathology as a consequence of environmental triggers. Although complement dysregulation is a...
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