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Article

Identification of Deleterious SNPs and Their Effects on Structural Level in CHRNA3 Gene.

Biochemical genetics - 1 Aug 2015

Chandramohan Vivek, Nagaraju Navya, Rathod Shrikant, Kaphle Anubhav, Muddapur Uday

Abstract excerpt

The aim of our study is to identify probable deleterious genetic variations that can alter the expression and the function of the CHRNA3 gene using in silico methods. Of the 2305 SNPs identified in the CHRNA3 gene, 115 were found to be non-synonymous and 12 and 15 nsSNPs were found to be in the 5' and 3' UTRs, respectively. Further, out of the 115 nsSNPs investigated, eight were predicted to be deleterious by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26002565
DOI: 10.1007/s10528-015-9676-y

Genes

CHRNA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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