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The association between TLR3 rs3775290 polymorphism and sporadic Parkinson's disease in Chinese Han population.

Neuroscience letters - 29 May 2020

Wang Jing, Liu Yumei, Liu Yang, Zhu Konghua, Xie Anmu

Abstract excerpt

Accumulating evidences have pointed out that neuroinflammation is involved in Parkinson's disease (PD) pathogenesis. Toll-like receptor 3 (TLR3), as a member of pattern-recognition receptors (PRRs), is known to play a pivotal role in inflammatory responses and immune responses. It was recently suggested that TLR3 was increased in the animal models of PD. The present study aimed to evaluate whether TLR3 gene...

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PMID: 32335220
DOI: 10.1016/j.neulet.2020.135005

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