Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between Carotid Intima-media Thickness and Aldehyde Dehydrogenase 2 Glu504Lys Polymorphism in Chinese Han with Essential Hypertension.

Chinese medical journal - 20 Jun 2016

Ma Xiao-Xiang, Zheng Shu-Zhan, Shu Yan, Wang Yong, Chen Xiao-Ping

Abstract excerpt

BACKGROUND: Aldehyde dehydrogenase 2 (ALDH2) is involved in the pathophysiological processes of cardiovascular diseases. Recent studies showed that mutant ALDH2 could increase oxidative stress and is a susceptible factor for hypertension. In addition, wild-type ALDH2 could improve the endothelial functions, therefore reducing the risk of developing atherosclerosis. The aim of the present study was to explore the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aldehyde Dehydrogenase, Mitochondrial
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carotid Intima-Media Thickness

Share to Essential Hypertension

Share to Hypertension

Share to Logistic Models

Share to Odds Ratio

Source

Open in PubMed Open full text

Identifiers

PMID: 27270535
DOI: 10.4103/0366-6999.183413
PMCID: PMC4910363

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between Carotid Intima-media Thickness and Aldehyde Dehydrogenase 2 Glu504Lys Polymorphism in Chinese Han with Essential Hypertension.PMID 27270535Read ↗

Association of the Glu504Lys polymorphism in the aldehyde dehydrogenase 2 gene with endothelium-dependent dilation disorder in Chinese Han patients with essential hypertension.Semantic proximity Read ↗

The Glu504Lys polymorphism of aldehyde dehydrogenase 2 contributes to development of coronary artery disease.Semantic proximity Read ↗

Association of ACE2 polymorphisms with susceptibility to essential hypertension and dyslipidemia in Xinjiang, ChinaSemantic proximity Read ↗

Association of Different Combinations of ALDH2 rs671, APOE rs429358, rs7412 Polymorphisms with Hypertension in Middle-Aged and Elderly People: A Case–Control StudySemantic proximity Read ↗

Association of angiotensin-converting enzyme 2 gene polymorphism and enzymatic activity with essential hypertension in different genderSemantic proximity Read ↗

The ALDH2 Glu504Lys polymorphism is associated with coronary artery disease in Han Chinese: Relation with endothelial ADMA levelsSemantic proximity Read ↗

Aldehyde dehydrogenase 2-associated metabolic abnormalities and cardiovascular diseases: current status, underlying mechanisms, and clinical recommendationsSemantic proximity Read ↗

ALDH2 Gene rs671 Polymorphism May Decrease the Risk of Essential Hypertension.Semantic proximity Read ↗

Association Between the Polymorphism of Aldehyde Dehydrogenase 2 Gene and Cerebral Infarction in a Hakka Population in Southern China.Semantic proximity Read ↗

Effect of alcohol and aldehyde dehydrogenase gene polymorphisms on alcohol-associated hypertension: the Guangzhou Biobank Cohort Study.Semantic proximity Read ↗

Association Between ALDH2 Polymorphisms and the Risk of Diabetes Mellitus in Hypertensive PatientsSemantic proximity Read ↗

The ALDH2 gene rs671 polymorphism is associated with cardiometabolic risk factors in East Asian population: an updated meta-analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.