Article
Meta-analysis of the IL23R and IL12B polymorphisms in multiple sclerosis.
The International journal of neuroscience - 1 Jan 2016
Huang Jian, Yang Yaqi, Zhou Fengmei, Liang Zibin, Kang Miaomiao, Kuang Ying, Li Feng
Abstract excerpt
PURPOSE: Polymorphisms in the genes encoding interleukin-23 receptor (IL23R) and the p40 subunit of IL-12/23 (IL12B) have been implicated in multiple sclerosis (MS) risk. However, results of different studies are inconsistent. Our aim was to perform a meta-analysis on this topic. METHODS: We assessed two variants (rs10889677 and rs7517847) of IL23R and the A1188C polymorphism (rs3212227) of IL12B. Electronic...
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