Article
Autoimmune hepatitis.
Seminars in immunopathology - 1 Sept 2009
Vergani Diego, Longhi Maria Serena, Bogdanos Dimitrios P, Ma Yun, Mieli-Vergani Giorgina
Abstract excerpt
Autoimmune hepatitis (AIH) is an inflammatory liver disease affecting mainly females and characterised histologically by interface hepatitis, biochemically by elevated transaminase levels and serologically by the presence of autoantibodies and increased levels of immunoglobulin G. AIH responds to immunosuppressive treatment, which should be instituted as soon as diagnosis is made. Seropositivity for smooth muscle...
Topics
- Animals
- Autoantibodies
- Female
- Genetic Predisposition to Disease
- Hepatitis, Autoimmune
- Humans
- Immunosuppressive Agents
- Liver
- Mice
- T-Lymphocytes, Cytotoxic
- T-Lymphocytes, Regulatory
