Article
Superoxide overproduction and kidney fibrosis: a new animal model.
Einstein (Sao Paulo, Brazil) - 1 Jan 2000
Guimarães-Souza Nadia Karina, Yamaleyeva Liliya Marsovna, Lu Baisong, Ramos Ana Claudia Mallet de Souza, Bishop Colin Edward, Andersson Karl Erik
Abstract excerpt
OBJECTIVE: To establish whether the mutation in the Immp2L gene induces renal fibrosis and whether aging exacerbates renal morphology in mice. METHODS: Female mutant mice with mutation in the inner mitochondrial membrane peptidase 2-like protein at 3 and 18 months of age were used. Renal fibrosis...
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