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Article

PDGFRα demarcates the cardiogenic clonogenic Sca1+ stem/progenitor cell in adult murine myocardium.

Nature communications - 18 May 2015

Noseda Michela, Harada Mutsuo, McSweeney Sara, Leja Thomas, Belian Elisa, Stuckey Daniel J, Abreu Paiva Marta S, Habib Josef, Macaulay Iain, de Smith Adam J, al-Beidh Farah, Sampson Robert, Lumbers R Thomas, Rao Pulivarthi, Harding Sian E, Blakemore Alexandra I F, Jacobsen Sten Eirik, Barahona Mauricio, Schneider Michael D

Abstract excerpt

Cardiac progenitor/stem cells in adult hearts represent an attractive therapeutic target for heart regeneration, though (inter)-relationships among reported cells remain obscure. Using single-cell qRT-PCR and clonal analyses, here we define four subpopulations of cardiac progenitor/stem cells in adult mouse myocardium all sharing stem cell antigen-1 (Sca1), based on side population (SP) phenotype, PECAM-1 (CD31)...

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Identifiers

PMID: 25980517
DOI: 10.1038/ncomms7930
PMCID: PMC4479024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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