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Article

SMYD3 contributes to a more aggressive phenotype of prostate cancer and targets Cyclin D2 through H4K20me3.

Oncotarget - 30 May 2015

Vieira Filipa Quintela, Costa-Pinheiro Pedro, Almeida-Rios Diogo, Graça Inês, Monteiro-Reis Sara, Simões-Sousa Susana, Carneiro Isa, Sousa Elsa Joana, Godinho Maria Inês, Baltazar Fátima, Henrique Rui, Jerónimo Carmen

Abstract excerpt

Prostate cancer (PCa) is one of the most incident cancers worldwide but clinical and pathological parameters have limited ability to discriminate between clinically significant and indolent PCa. Altered expression of histone methyltransferases and histone methylation patterns are involved in prostate carcinogenesis. SMYD3 transcript levels have prognostic value and discriminate among PCa with different clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25980436
DOI: 10.18632/oncotarget.3767
PMCID: PMC4537039

Genes

SMYD3
SET
CCND2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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