Article
[Detection of p16 by fluorescence in-situ hybridization and immunohistochemistry in malignant mesothelioma].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Apr 2015
Liu Ying, Chen Xiaoling, Ding Ningning, Xu Wenxiang, Yang Hong, Chen Xuechen
Abstract excerpt
OBJECTIVE: To study the role of p16 gene mutation status as detected by fluorescence in-situ hybridization (FISH) and p16 protein expression as detected by immunohistochemistry in differential diagnosis of malignant mesothelioma and benign mesothelial hyperplasia. METHODS: p16 gene mutation status and protein expression were detected by FISH and immunohistochemistry respectively in 55 cases of pleural malignant...
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