A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies FLT3-Mutated Clones in Acute Myeloid Leukemia.

doi:10.1158/1078-0432.CCR-14-3186

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Article

A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies FLT3-Mutated Clones in Acute Myeloid Leukemia.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2015

Angelini Daniela F, Ottone Tiziana, Guerrera Gisella, Lavorgna Serena, Cittadini Michela, Buccisano Francesco, De Bardi Marco, Gargano Francesca, Maurillo Luca, Divona Mariadomenica, Noguera Nélida I, Consalvo Maria Irno, Borsellino Giovanna, Bernardi Giorgio, Amadori Sergio, Venditti Adriano, Battistini Luca, Lo-Coco Francesco

Abstract excerpt

PURPOSE: We evaluated leukemia-associated immunophenotypes (LAIP) and their correlation with fms-like tyrosine kinase 3 (FLT3) and nucleophosmin (NPM1) gene mutational status in order to contribute a better identification of patients at highest risk of relapse in acute myeloid leukemia (AML). EXPERIMENTAL DESIGN: Bone marrow samples from 132 patients with AML were analyzed by nine-color multiparametric flow...

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PMID: 25957287
DOI: 10.1158/1078-0432.CCR-14-3186

Genes

FLT3
NPM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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