Article
Impacts of EGFR mutation and EGFR-TKIs on incidence of brain metastases in advanced non-squamous NSCLC.
Clinical neurology and neurosurgery - 1 Sept 2017
Wang Bao-Xiao, Ou Wei, Mao Xiao-Yong, Liu Zui, Wu Hui-Qi, Wang Si-Yu
Abstract excerpt
OBJECTIVE: Brain metastases remain lethal in lung cancer patients. The impacts of epidermal growth factor receptor (EGFR) mutations and EGFR tyrosine kinase inhibitors (TKIs) on the incidence of brain metastases in patients with advanced non-squamous non-small cell lung cancer (NSCLC) are still uncertain. PATIENTS AND METHODS: A total of 1672 patients with advanced non-squamous NSCLC with a definitive report on...
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