Article
The association of interleukin-16 gene polymorphisms with IL-16 serum levels and risk of nasopharyngeal carcinoma in a Chinese population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2014
Qin Xue, Peng Qiliu, Lao Xiaoxia, Chen Zhiping, Lu Yu, Lao Xianjun, Mo Cuiju, Sui Jingzhe, Wu Junrong, Zhai Limin, Yang Shi, Li Shan, Zhao Jinmin
Abstract excerpt
Interleukin (IL)-16 plays a fundamental role in inflammatory diseases, as well as in the development and progression of tumors. Genetic variation in DNA sequence of IL16 gene may lead to altered cytokine production and/or activity, and this variation may modulate an individual's susceptibility to nasopharyngeal carcinoma (NPC). To test this hypothesis, we investigated the association of IL16 gene polymorphisms...
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