Article
RAX2: a genome-wide detection method of condition-associated transcription variation.
Nucleic acids research - 3 Sept 2015
Tan Yuan-De, Deng Jixin, Neilson Joel R
Abstract excerpt
Most mammalian genes have mRNA variants due to alternative promoter usage, alternative splicing, and alternative cleavage and polyadenylation. Expression of alternative RNA isoforms has been found to be associated with tumorigenesis, proliferation and differentiation. Detection of condition-associated transcription variation requires association methods. Traditional association methods such as Pearson chi-square...
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