Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparison of Genetic and Epigenetic Alterations of Primary Tumors and Matched Plasma Samples in Patients with Colorectal Cancer

6 May 2015

Abstract excerpt

BACKGROUND: Although recent advances in circulating DNA analysis allow the prediction of tumor genomes by noninvasive means, some challenges remain, which limit the widespread introduction of cfDNA in cancer diagnostics. We analyzed the status of the two best characterized colorectal cancer (CRC) genetic and epigenetic alterations in a cohort of CRC patients, and then compared the degree to which the two patterns...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Colorectal Cancer Treatments and Studies
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25946211
DOI: 10.1371/journal.pone.0126417

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparison of Genetic and Epigenetic Alterations of Primary Tumors and Matched Plasma Samples in Patients with Colorectal CancerPMID 25946211Read ↗

Circulating-tumour DNA methylation of HAND1 gene: a promising biomarker in early detection of colorectal cancerSemantic proximity Read ↗

Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer.Semantic proximity Read ↗

Circulating Methylated SEPT9 DNA in Plasma Is a Biomarker for Colorectal CancerSemantic proximity Read ↗

Epigenetic Regulation Explains The Functionality Behind Colon Cancer Specific Biomarker Septin9Semantic proximity Read ↗

Advance in plasma SEPT9 gene methylation assay for colorectal cancer early detectionSemantic proximity Read ↗

DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancerSemantic proximity Read ↗

Sensitive Detection of Colorectal Cancer in Peripheral Blood by Septin 9 DNA Methylation AssaySemantic proximity Read ↗

Circulating DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancerSemantic proximity Read ↗

Plasma mSEPT9: A Novel Circulating Cell-free DNA-Based Epigenetic Biomarker to Diagnose Hepatocellular CarcinomaSemantic proximity Read ↗

Detection of Methylated Septin 9 in Tissue and Plasma of Colorectal Patients with Neoplasia and the Relationship to the Amount of Circulating Cell-Free DNASemantic proximity Read ↗

The potential of PIK3CA, KRAS, BRAF, and APC hotspot mutations as a non-invasive detection method for colorectal cancer.Semantic proximity Read ↗

A novel DNA methylation panel accurately detects colorectal cancer independently of molecular pathway.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.