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Article

A novel DNA methylation panel accurately detects colorectal cancer independently of molecular pathway.

Journal of translational medicine - 27 Feb 2018

Freitas Micaela, Ferreira Fábio, Carvalho Sónia, Silva Fernanda, Lopes Paula, Antunes Luís, Salta Sofia, Diniz Francisca, Santos Lúcio Lara, Videira José Flávio, Henrique Rui, Jerónimo Carmen

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is one of the most incident cancers, associated with significant morbidity and mortality, and usually classified into three main molecular pathways: chromosomal instability, microsatellite instability (MSI) and CpG island methylator phenotype (CIMP). Currently, available screening methods are either costly or of limited specificity, impairing global implementation. More...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29486770
DOI: 10.1186/s12967-018-1415-9
PMCID: PMC6389195

Genes

MGMT
IGF2
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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