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The Controversial Role of Autophagy in Ewing Sarcoma Pathogenesis—Current Treatment Options

26 Feb 2021

Abstract excerpt

(Friend leukemia virus integration site 1) genes, leading to an EWS-FLI1 fused protein, which is associated with autophagy, a homeostatic and catabolic mechanism under normal and pathological conditions. Following such interesting and controversial data regarding autophagy in ES, many clinical trials using modulators of autophagy are now underway in this field. In the present review, we summarize current data and...

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PMID: 33652741
DOI: 10.3390/biom11030355

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