Article
Genomic analysis reveals the molecular basis for capsule loss in the group B Streptococcus population.
PloS one - 1 Jan 2015
Rosini Roberto, Campisi Edmondo, De Chiara Matteo, Tettelin Hervé, Rinaudo Daniela, Toniolo Chiara, Metruccio Matteo, Guidotti Silvia, Sørensen Uffe B Skov, Kilian Mogens, Ramirez Mario, Janulczyk Robert, Donati Claudio, Grandi Guido, Margarit Immaculada
Abstract excerpt
The human and bovine bacterial pathogen Streptococcus agalactiae (Group B Streptococcus, GBS) expresses a thick polysaccharide capsule that constitutes a major virulence factor and vaccine target. GBS can be classified into ten distinct serotypes differing in the chemical composition of their capsular polysaccharide. However, non-typeable strains that do not react with anti-capsular sera are frequently isolated...
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