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CYP2E1 Rsa Ι/Pst Ι polymorphism and lung cancer susceptibility: a meta-analysis involving 10,947 subjects.

Journal of cellular and molecular medicine - 1 Sept 2015

Shen Ze-Tian, Wu Xin-Hu, Li Bing, Shen Jun-shu, Wang Zhen, Li Jing, Zhu Xi-Xu

Abstract excerpt

Many studies have examined the association between the CYP2E1 Rsa Ι/Pst Ι (rs3813867) polymorphism gene polymorphisms and lung cancer risk in various populations, but their results have been inconsistent. The PubMed and CNKI database was searched for case-control studies published up to October 2013. Data were extracted and pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated. In this...

Topics

Alleles
Cytochrome P-450 CYP2E1
Genetic Predisposition to Disease
Humans
Lung Neoplasms
Odds Ratio
Polymorphism, Genetic
Risk Factors

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Identifiers

PMID: 25945422
DOI: 10.1111/jcmm.12579
PMCID: PMC4568918

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