Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aberrant TGFβ Signalling Contributes to Dysregulation of Sphingolipid Metabolism in Intrauterine Growth Restriction

5 May 2015

Abstract excerpt

CONTEXT: Sphingolipids function as key bioactive mediators that regulate cell fate events in a variety of systems. Disruptions in sphingolipid metabolism characterize several human pathologies. OBJECTIVE: In the present study we examined sphingolipid metabolism in intrauterine growth restriction (IUGR), a severe disorder complicating 4-7% of pregnancies at increased risk of perinatal morbidity and mortality,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pregnancy and preeclampsia studies
Share to Preterm Birth and Chorioamnionitis
Share to Sphingolipid Metabolism and Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25942476
DOI: 10.1210/jc.2015-1288

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aberrant TGFβ Signalling Contributes to Dysregulation of Sphingolipid Metabolism in Intrauterine Growth RestrictionPMID 25942476Read ↗

Maternal disturbance in activated sphingolipid metabolism causes pregnancy loss in miceSemantic proximity Read ↗

TGFβ signalling: a nexus between inflammation, placental health and preeclampsia throughout pregnancySemantic proximity Read ↗

Tumor Necrosis Factor-α Induces a Preeclamptic-like Phenotype in Placental Villi via Sphingosine Kinase 1 Activation.Semantic proximity Read ↗

The TGFβ Family in Human Placental Development at the Fetal-Maternal InterfaceSemantic proximity Read ↗

Intrauterine growth restriction, human placental development and trophoblast cell deathSemantic proximity Read ↗

Decreased <i>STAT3</i> in human idiopathic fetal growth restriction contributes to trophoblast dysfunctionSemantic proximity Read ↗

Lysophosphatidylcholine Impairs the Mitochondria Homeostasis Leading to Trophoblast Dysfunction in Gestational Diabetes MellitusSemantic proximity Read ↗

Molecular mechanisms of intrauterine growth restrictionSemantic proximity Read ↗

Roles of TGF-β1 in Viral Infection during Pregnancy: Research Update and PerspectivesSemantic proximity Read ↗

Involvement of MAPK Signalling in Human Villous Trophoblast DifferentiationSemantic proximity Read ↗

The Placental NLRP3 Inflammasome and Its Downstream Targets, Caspase-1 and Interleukin-6, Are Increased in Human Fetal Growth Restriction: Implications for Aberrant Inflammation-Induced Trophoblast DysfunctionSemantic proximity Read ↗

RNA Sequencing Exposes Adaptive and Immune Responses to Intrauterine Growth Restriction in Fetal Sheep IsletsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.