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Article

NKp46 regulates the production of serine proteases and IL-22 in human mast cells in urticaria pigmentosa.

Experimental dermatology - 1 Sept 2015

Ueshima Chiyuki, Kataoka Tatsuki R, Hirata Masahiro, Koyanagi Itsuko, Honda Tetsuya, Tsuruyama Tatsuaki, Okayama Yoshimichi, Seiyama Akitoshi, Haga Hironori

Abstract excerpt

NKp46 (natural cytotoxic receptor 1/CD335) is expressed on natural killer cells and Th2-type innate lymphocytes. However, NKp46 expression in human mast cells has not yet been reported. Here, we explored the expression of, and possible role played by, NKp46 in such cells. NKp46 protein was expressed in human mast cells in urticaria pigmentosa principally of the tryptase-positive/chymase-negative type (MCT), but...

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PMID: 25940096
DOI: 10.1111/exd.12741

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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