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Article

XRCC1 Polymorphisms and Urinary 8-Hydroxydeoxyguanine Levels Are Associated with Urothelial Carcinoma.

PloS one - 1 Jan 2015

Chiang Chien-I, Huang Ya-Li, Huang Chao-Yuan, Shiue Horng-Sheng, Chen Wei-Jen, Pu Yeong-Shiau, Lin Ying-Chin, Hsueh Yu-Mei

Abstract excerpt

The aim of this study was to examine the associations between the combined effects of urinary 8-Hydroxydeoxyguanine (8-OHdG) level and polymorphisms of XRCC1 Arg194Trp and XRCC1 Arg399Gln on the risk of urothelial carcinoma (UC). We conducted a hospital-based case-control study that included 168 cases of UC and 336 age- and gender-matched healthy controls. We used polymerase chain reaction and restriction...

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Source

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Identifiers

PMID: 25938407
DOI: 10.1371/journal.pone.0124066
PMCID: PMC4418762

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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XRCC1 Polymorphisms and Urinary 8-Hydroxydeoxyguanine Levels Are Associated with Urothelial Carcinoma.PMID 25938407Read ↗

XRCC1 Arg194Trp and Arg399Gln polymorphisms and arsenic methylation capacity are associated with urothelial carcinoma.Semantic proximity Read ↗

XRCC1 polymorphisms and cancer risk: a meta-analysis of 38 case-control studies.Semantic proximity Read ↗

The polymorphism XRCC1 Arg194Trp and 8-hydroxydeoxyguanosine increased susceptibility to arsenic-related renal cell carcinoma.Semantic proximity Read ↗

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Genetic polymorphisms of XRCC1, alcohol consumption, and the risk of colorectal cancer in Japan.Semantic proximity Read ↗

Meta-analysis demonstrates no association between XRCC1 Arg399Gln polymorphism and bladder cancer risk.Semantic proximity Read ↗

XRCC1 genetic polymorphisms and bladder cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

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A meta-analysis on XRCC1 R399Q and R194W polymorphisms, smoking and bladder cancer risk.Semantic proximity Read ↗

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