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Article

Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes.

Blood - 2 Jul 2015

Steensma David P, Bejar Rafael, Jaiswal Siddhartha, Lindsley R Coleman, Sekeres Mikkael A, Hasserjian Robert P, Ebert Benjamin L

Abstract excerpt

Recent genetic analyses of large populations have revealed that somatic mutations in hematopoietic cells leading to clonal expansion are commonly acquired during human aging. Clonally restricted hematopoiesis is associated with an increased risk of subsequent diagnosis of myeloid or lymphoid neoplasia and increased all-cause mortality. Although myelodysplastic syndromes (MDS) are defined by cytopenias, dysplastic...

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Identifiers

PMID: 25931582
DOI: 10.1182/blood-2015-03-631747
PMCID: PMC4624443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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