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DNA Methylation-Based Testing in Peripheral Blood Mononuclear Cells Enables Accurate and Early Detection of Colorectal Cancer

21 Aug 2023

Abstract excerpt

An effective blood-based method for the diagnosis of colorectal cancer has not yet been developed. Molecular alterations of immune cells occur early in tumorigenesis, providing the theoretical underpinning for early cancer diagnosis based on immune cell profiling. Therefore, we aimed to develop an effective detection method based on peripheral blood mononuclear cells (PBMC) to improve the diagnosis of colorectal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37602818
DOI: 10.1158/0008-5472.can-22-3402

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