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Article

Lack of associations of neuregulin 1 variations with schizophrenia and smooth pursuit eye movement abnormality in a Korean population.

Journal of molecular neuroscience : MN - 1 Mar 2012

Kim Jeong-Hyun, Park Byung-Lae, Pasaje Charisse Flerida A, Bae Joon Seol, Park Chul Soo, Cha Boseok, Kim Bong-Jo, Lee Migyung, Choi Woo Hyuk, Shin Tae-Min, Choi Ihn-Geun, Hwang Jaeuk, Koh Insong, Woo Sung-Il, Shin Hyoung Doo

Abstract excerpt

Schizophrenia is a serious and disabling mental disorder with a high heritability rate. The human neuregulin 1 (NRG1) on 8p12 has been implicated as a candidate gene for schizophrenia. However, controversial results of the associations of NRG1 polymorphisms with schizophrenia and related phenotypes have been reported. In this study, four NRG1 single nucleotide polymorphisms, three in the promoter region, and one...

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Identifiers

PMID: 21858616
DOI: 10.1007/s12031-011-9619-y

Genes

NRG1

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