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Article

Cystic Fibrosis from Laboratory to Bedside: The Role of A20 in NF-κB-Mediated Inflammation.

Medical principles and practice : international journal of the Kuwait University, Health Science Centre - 1 Jan 2015

Bannon Aidan, Zhang Shu-Dong, Schock Bettina C, Ennis Madeleine

Abstract excerpt

Cystic fibrosis (CF) is a lifelong, inflammatory multi-organ disease and the most common lethal, genetic condition in Caucasian populations, with a median survival rate of 41.5 years. Pulmonary disease, characterized by infective exacerbations, bronchiectasis and increasing airway insufficiency is the most serious manifestation of this disease process, currently responsible for over 80% of CF deaths. Chronic...

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Source

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Identifiers

PMID: 25925366
DOI: 10.1159/000381423
PMCID: PMC5588248

Genes

TNF
TRAF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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