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Prevalence of BRCA1 and BRCA2 Mutations Among High-Risk Saudi Patients With Breast Cancer.

Journal of global oncology - 1 Aug 2018

Abulkhair Omalkhair, Al Balwi Mohammed, Makram Ola, Alsubaie Lamia, Faris Medhat, Shehata Hussam, Hashim Ahmed, Arun Banu, Saadeddin Ahmed, Ibrahim Ezzeldin

Abstract excerpt

Purpose Over the past three decades, the incidence rate of breast cancer (BC) among Arab women has continually increased. However, data on the prevalence of BRCA1/2 mutations are scarce. Although the population in Saudi Arabia is at large homogeneous and consanguinity is common, especially in the central, eastern, and southern regions of the country, the prevalence of BRCA1 and BRCA2 mutations and the...

Topics

BRCA1 Protein
BRCA2 Protein
Breast Neoplasms
Female
Humans
Middle Aged
Mutation
Neoplasm Staging
Risk Factors
Saudi Arabia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30199306
DOI: 10.1200/JGO.18.00066
PMCID: PMC6223490

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