Article
Pattern of SMARCB1 (INI1) and SMARCA4 (BRG1) in poorly differentiated endometrioid adenocarcinoma of the uterus: analysis of a series with emphasis on a novel SMARCA4-deficient dedifferentiated rhabdoid variant.
Annals of diagnostic pathology - 1 Aug 2015
Strehl Johanna D, Wachter David L, Fiedler Jutta, Heimerl Engelbert, Beckmann Matthias W, Hartmann Arndt, Agaimy Abbas
Abstract excerpt
The role of the switch/sucrose nonfermenting chromatin remodeling complex in the initiation and progression of cancer is emerging. In the female genital tract, only ovarian small cell carcinoma, hypercalcemic type harbors recurrent inactivating SMARCA4 mutations. Otherwise, only rare case reports...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.