Article
KALRN Rare and Common Variants and Susceptibility to Ischemic Stroke in Chinese Han Population.
Neuromolecular medicine - 1 Sept 2015
Dang Meizheng, Wang Zhenzhen, Zhang Ruyou, Li Xiaoying, Peng Yanqing, Han Xuesong, Sun Litao, Tian Jiawei
Abstract excerpt
Stroke is the second most common cause of mortality worldwide, and it is a major cause of physical disability. Several genome-wide association studies have yielded numerous common variants which increase the risk of ischemic stroke, including the Kalirin-coding gene, KALRN. KALRN strongly associates with early-onset coronary artery disease and atherosclerosis and plays an important role in stroke in the European...
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