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Article

Pseudogenization of sopA and sopE2 is functionally linked and contributes to virulence of Salmonella enterica serovar Typhi.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2015

Valenzuela L M, Hidalgo A A, Rodríguez L, Urrutia I M, Ortega A P, Villagra N A, Paredes-Sabja D, Calderón I L, Gil F, Saavedra C P, Mora G C, Fuentes J A

Abstract excerpt

The difference in host range between Salmonella enterica serovar Typhimurium (S. Typhimurium) and S. enterica serovar Typhi (S. Typhi) can be partially attributed to pseudogenes. Pseudogenes are genomic segments homologous to functional genes that do not encode functional products due to the presence of genetic defects. S. Typhi lacks several protein effectors implicated in invasion or other important processes...

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Identifiers

PMID: 25913156
DOI: 10.1016/j.meegid.2015.04.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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