Article
S. Typhimurium sseJ gene decreases the S. Typhi cytotoxicity toward cultured epithelial cells.
BMC microbiology - 7 Dec 2010
Trombert A Nicole, Berrocal Liliana, Fuentes Juan A, Mora Guido C
Abstract excerpt
BACKGROUND: Salmonella enterica serovar Typhi and Typhimurium are closely related serovars as indicated by >96% DNA sequence identity between shared genes. Nevertheless, S. Typhi is a strictly human-specific pathogen causing a systemic disease, typhoid fever. In contrast, S. Typhimurium is a broad host range pathogen causing only a self-limited gastroenteritis in immunocompetent humans. We hypothesize that these...
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