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Host restriction of Salmonella enterica serotype Typhi is not caused by functional alteration of SipA, SopB, or SopD.

Infection and immunity - 1 Dec 2005

Raffatellu Manuela, Sun Yao-Hui, Wilson R Paul, Tran Quynh T, Chessa Daniela, Andrews-Polymenis Helene L, Lawhon Sara D, Figueiredo Josely F, Tsolis Renée M, Adams L Garry, Bäumler Andreas J

Abstract excerpt

Salmonella enterica serotype Typhi is a strictly human adapted pathogen that does not cause disease in nonprimate vertebrate hosts, while Salmonella enterica serotype Typhimurium is a broad-host-range pathogen. Serotype Typhi lacks some of the proteins (effectors) exported by the invasion-associated type III secretion system that are required by serotype Typhimurium for eliciting fluid secretion and inflammation...

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Identifiers

PMID: 16299271
DOI: 10.1128/IAI.73.12.7817-7826.2005
PMCID: PMC1307101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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