Article
Pin1 liberates the human immunodeficiency virus type-1 (HIV-1): Must we stop it?
Gene - 1 Jul 2015
Hou Hai, Wang Jing-Zhang, Liu Bao-Guo, Zhang Ting
Abstract excerpt
Acquired immune deficiency syndrome (AIDS) is mainly caused by the human immunodeficiency virus type-1 (HIV-1). To our knowledge, this is the first review focusing on the vital role of Pin1 in the infection of HIV-1 and the development of AIDS. We and others have demonstrated that Pin1, the only known cis-to-trans isomerase recognizing the pThr/pSer-Pro motifs in proteins, plays striking roles in several human...
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