Article
Identification and functional characterization of the CYP51 gene from the yeast Xanthophyllomyces dendrorhous that is involved in ergosterol biosynthesis.
BMC microbiology - 25 Apr 2015
Leiva Kritsye, Werner Nicole, Sepúlveda Dionisia, Barahona Salvador, Baeza Marcelo, Cifuentes Víctor, Alcaíno Jennifer
Abstract excerpt
BACKGROUND: Xanthophyllomyces dendrorhous is a basidiomycetous yeast that synthesizes astaxanthin, a carotenoid with great biotechnological impact. The ergosterol and carotenoid synthetic pathways derive from the mevalonate pathway and involve cytochrome P450 enzymes. Among these enzymes, the CYP51 family, which is involved in ergosterol biosynthesis, is one of the most remarkable that has C14-demethylase...
Topics
- Basidiomycota
- Carotenoids
- DNA, Fungal
- Ergosterol
- Exons
- Genetic Complementation Test
- Molecular Sequence Data
- Mutation
- Saccharomyces cerevisiae
- Sequence Analysis, DNA
- Sequence Homology, Amino Acid
- Sterol 14-Demethylase