Article
Characterization of the sterol 14α-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function.
The New phytologist - 1 May 2013
Fan Jieru, Urban Martin, Parker Josie E, Brewer Helen C, Kelly Steven L, Hammond-Kosack Kim E, Fraaije Bart A, Liu Xili, Cools Hans J
Abstract excerpt
CYP51 encodes the cytochrome P450 sterol 14α-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides. In Fusarium species, including pathogens of humans and plants, three CYP51 paralogues have been identified with one unique to the genus. Currently, the functions of these three genes and the rationale for their conservation within the genus Fusarium are unknown. Three Fusarium...
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