Article
Extensive Within-Host Diversity in Fecally Carried Extended-Spectrum-Beta-Lactamase-Producing Escherichia coli Isolates: Implications for Transmission Analyses.
Journal of clinical microbiology - 1 Jul 2015
Stoesser N, Sheppard A E, Moore C E, Golubchik T, Parry C M, Nget P, Saroeun M, Day N P J, Giess A, Johnson J R, Peto T E A, Crook D W, Walker A S
Abstract excerpt
Studies of the transmission epidemiology of antimicrobial-resistant Escherichia coli, such as strains harboring extended-spectrum beta-lactamase (ESBL) genes, frequently use selective culture of rectal surveillance swabs to identify isolates for molecular epidemiological investigation. Typically, only single colonies are evaluated, which risks underestimating species diversity and transmission events. We...
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