Article
Capturing the cloud of diversity reveals complexity and heterogeneity of MRSA carriage, infection and transmission.
Nature communications - 27 Mar 2015
Paterson Gavin K, Harrison Ewan M, Murray Gemma G R, Welch John J, Warland James H, Holden Matthew T G, Morgan Fiona J E, Ba Xiaoliang, Koop Gerrit, Harris Simon R, Maskell Duncan J, Peacock Sharon J, Herrtage Michael E, Parkhill Julian, Holmes Mark A
Abstract excerpt
Genome sequencing is revolutionizing clinical microbiology and our understanding of infectious diseases. Previous studies have largely relied on the sequencing of a single isolate from each individual. However, it is not clear what degree of bacterial diversity exists within, and is transmitted between individuals. Understanding this 'cloud of diversity' is key to accurate identification of transmission pathways....
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