Article
Diversity of Class 1 Integron Gene Cassette Rearrangements Selected under Antibiotic Pressure.
Journal of bacteriology - 1 Jul 2015
Barraud Olivier, Ploy Marie-Cécile
Abstract excerpt
UNLABELLED: Integrons are bacterial genetic elements able to capture and express genes contained within mobile gene cassettes. Gene cassettes are expressed via a Pc promoter and can be excised from or integrated into the integron by integrase IntI. Although the mechanisms of gene cassette integration and excision are well known, the kinetics and modes of gene cassette shuffling leading to new gene cassette arrays...
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