Article

Pre-stroke physical activity and Val66Met (rs6265) genotype of <i>BDNF</i> gene correlate with the post-stroke cognitive outcome: a prospective cohort study

2026-03-20

Abstract excerpt

<h4>Background</h4> Pre-stroke physical activity may protect against post-stroke cognitive impairment (PSCI) via neuroplastic mechanisms including BDNF signalling. However, evidence in stroke survivors and the modifying role of the BDNF Val66Met polymorphism remain limited. <h4>Methods</h4> In this prospective single-centre cohort, 97 patients with ischaemic stroke underwent detailed neuropsychological assessm...

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Literature Corpus work: 7cdb7ac4-6392-53db-8c19-4157269a2384
DOI: 10.64898/2026.03.19.26348718

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