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Article

Increased microRNA-34b and -34c predominantly expressed in stromal tissues is associated with poor prognosis in human colon cancer.

PloS one - 1 Jan 2015

Hiyoshi Yukiharu, Schetter Aaron J, Okayama Hirokazu, Inamura Kentaro, Anami Katsuhiro, Nguyen Giang H, Horikawa Izumi, Hawkes Jason E, Bowman Elise D, Leung Suet Yi, Harris Curtis C

Abstract excerpt

The microRNA-34 family (miR-34a, -34b and -34c) have been reported to be tumor suppressor microRNAs (miRNAs) that are regulated by the TP53 and DNA hypermethylation. However, the expression, regulation, and prognostic value of the miR-34 family have not been systematically studied in colon cancer...

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Identifiers

PMID: 25894979
DOI: 10.1371/journal.pone.0124899
PMCID: PMC4404052

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25894979-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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