Article
Analysis of microRNA-34a expression profile and rs2666433 variant in colorectal cancer: a pilot study.
Scientific reports - 9 Oct 2020
Fawzy Manal S, Ibrahiem Afaf T, AlSel Baraah T Abu, Alghamdi Saleh A, Toraih Eman A
Abstract excerpt
MicroRNAs (miRNAs) are implicated in every stage of carcinogenesis and play an essential role as genetic biomarkers of cancer. We aimed to evaluate microRNA-34a gene (MIR34A) expression in colorectal cancer (CRC) tissues compared with non-cancer one and to preliminarily explore the association of one related variant to CRC risk. A total of 116 paraffin-embedded colon specimens were enrolled. MiR-34a was...
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