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Article

Positively Charged Oligo[Poly(Ethylene Glycol) Fumarate] Scaffold Implantation Results in a Permissive Lesion Environment after Spinal Cord Injury in Rat.

Tissue engineering. Part A - 1 Jul 2015

Hakim Jeffrey S, Esmaeili Rad Melika, Grahn Peter J, Chen Bingkun K, Knight Andrew M, Schmeichel Ann M, Isaq Nasro A, Dadsetan Mahrokh, Yaszemski Michael J, Windebank Anthony J

Abstract excerpt

Positively charged oligo[poly(ethylene glycol) fumarate] (OPF+) scaffolds loaded with Schwann cells bridge spinal cord injury (SCI) lesions and support axonal regeneration in rat. The regeneration achieved is not sufficient for inducing functional recovery. Attempts to increase regeneration would benefit from understanding the effects of the scaffold and transplanted cells on lesion environment. We conducted...

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Identifiers

PMID: 25891264
DOI: 10.1089/ten.TEA.2015.0019
PMCID: PMC4507127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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