Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expanding Primary Metabolism Helps Generate the Metabolic Robustness To Facilitate Antibiotic Biosynthesis in Streptomyces

5 Feb 2018

Abstract excerpt

ABSTRACT The expansion of the genetic repertoire of an organism by gene duplication or horizontal gene transfer (HGT) can aid adaptation. Streptomyces bacteria are prolific producers of bioactive specialized metabolites that have adaptive functions in nature and have found extensive utility in human medicine. While the biosynthesis of these specialized metabolites is directed by dedicated biosynthetic gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biochemical and Molecular Research
Share to Microbial Metabolic Engineering and Bioproduction
Share to Microbial Natural Products and Biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29437921
DOI: 10.1128/mbio.02283-17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expanding Primary Metabolism Helps Generate the Metabolic Robustness To Facilitate Antibiotic Biosynthesis in StreptomycesPMID 29437921Read ↗

Expanding gene families helps generate the metabolic robustness required for antibiotic biosynthesisSemantic proximity Read ↗

Systems biology approach for metabolomic engineering in Streptomyces : the Phosphoenolpyruvate-Pyruvate-Oxaloacetate nodeSemantic proximity Read ↗

Differential transcription of expanded gene families in central carbon metabolism of <i>Streptomyces coelicolor</i> A3(2)Semantic proximity Read ↗

Intra- and inter-biosynthetic gene cluster allelic variation as drivers of chemical diversification in Streptomyces.Semantic proximity Read ↗

Comparative Genomics Reveals the Core and Accessory Genomes of Streptomyces Species.Semantic proximity Read ↗

Pangenome mining of the Streptomyces genus redefines species’ biosynthetic potentialSemantic proximity Read ↗

Evolution and Ecology of StreptomycesSemantic proximity Read ↗

Phylogenomic analysis of natural products biosynthetic gene clusters allows discovery of arseno-organic metabolites in model streptomycetesSemantic proximity Read ↗

Genome mining of biosynthetic and chemotherapeutic gene clusters in Streptomyces bacteriaSemantic proximity Read ↗

Toward Systems Metabolic Engineering of Streptomycetes for Secondary Metabolites ProductionSemantic proximity Read ↗

Taxonomic and Metabolic Incongruence in the Ancient Genus StreptomycesSemantic proximity Read ↗

Mining and manipulation of antibiotic biosynthesis in StreptomycesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.