Article
How do SNP ascertainment schemes and population demographics affect inferences about population history?
BMC genomics - 3 Apr 2015
McTavish Emily Jane, Hillis David M
Abstract excerpt
BACKGROUND: The selection of variable sites for inclusion in genomic analyses can influence results, especially when exemplar populations are used to determine polymorphic sites. We tested the impact of ascertainment bias on the inference of population genetic parameters using empirical and simulated data representing the three major continental groups of cattle: European, African, and Indian. We simulated data...
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