Article
Loss of gene function and evolution of human phenotypes.
BMB reports - 1 Jul 2015
Oh Hye Ji, Choi Dongjin, Goh Chul Jun, Hahn Yoonsoo
Abstract excerpt
Humans have acquired many distinct evolutionary traits after the human-chimpanzee divergence. These phenotypes have resulted from genetic changes that occurred in the human genome and were retained by natural selection. Comparative primate genome analyses reveal that loss-of-function mutations are common in the human genome. Some of these gene inactivation events were revealed to be associated with the emergence...
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