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Article

Cell-composition effects in the analysis of DNA methylation array data: a mathematical perspective.

BMC bioinformatics - 21 Mar 2015

Houseman E Andres, Kelsey Karl T, Wiencke John K, Marsit Carmen J

Abstract excerpt

BACKGROUND: The impact of cell-composition effects in analysis of DNA methylation data is now widely appreciated. With the availability of a reference data set consisting of DNA methylation measurements on isolated cell types, it is possible to impute cell proportions and adjust for them, but there is increasing interest in methods that adjust for cell composition effects when reference sets are incomplete or...

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Identifiers

PMID: 25887114
DOI: 10.1186/s12859-015-0527-y
PMCID: PMC4392865

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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