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Article

COP1, the negative regulator of ETV1, influences prognosis in triple-negative breast cancer

14 Mar 2015

Abstract excerpt

BACKGROUND: ETS variant 1 (ETV1) and E3 ubiquitin ligase constitutive photomorphogenetic 1 (COP1) have been proposed to be a pair of oncogene and tumor suppressor. However, the co-existing status of ETV1 and COP1 in triple-negative breast cancer (TNBC) and their predictive role in determining the patient's outcome are uncertain. METHODS: We examined the abundance of COP1 and ETV1 proteins and their...

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PMID: 25884720
DOI: 10.1186/s12885-015-1151-y

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